Protease-activated receptors are potential regulators in the development of arterial endofibrosis in high-performance athletes

01 april 2019 Objective: High-performance athletes can develop symptomatic arterial flow restriction during exercise caused by endofibrosis. The pathogenesis is poorly understood; however, coagulation enzymes, such as tissue factor (TF) and coagulation factor Xa,...

The biology of external iliac artery endofibosis: What can we learn from this disease to help us treat other fibroproliferative arteriopathies?

01 april 2019 Arterial endofibrosis is a vascular disease that typically affects the external iliac artery in young patients who undergo extreme exercise, mainly bicyclists.1 The diagnosis is indirectly suspected when these extreme athletes undergo ankle-brachial...